SCI 投稿全过程信件模板一览
一、最初投稿Cover letter
Dear Editors:
We would like to submit the enclosed manuscript entitled “Paper Title”, which we wish to be considered for publication in “Journal Name”. No conflict of interest exits in the submission of this manuscript, and manuscript is approved by all authors for publication. I would like to declare on behalf of my co-authors that the work described was original research that has not been published previously, and not under consideration for publication elsewhere, in whole or in part. All the authors listed have approved the manuscript that is enclosed.
In this work, we evaluated ……(简要介绍一下论文的创新性). I hope this paper is suitable for “Journal Name”.
The following is a list of possible reviewers for your consideration:
1) Name A E-mail: ××××@××××
2) Name B E-mail: ××××@××××
We deeply appreciate your consideration of our manuscript, and we look forward to receiving comments from the reviewers. If you have any queries, please don’t hesitate to contact me at the address below.
Thank you and best regards.
Yours sincerely,
××××××
Corresponding author:
Name: ×××
E-mail: ××××@××××
二、催稿信
Dear Prof. ×××:
Sorry for disturbing you. I am not sure if it is the right time to contact you to inquire about the status of my submitted manuscript titled “Paper Title”. (ID: 文章稿号), although the status of “With Editor” has been lasting for more than two months, since submitted to journal three months ago. I am just wondering that my manuscript has been sent to reviewers or not?
I would be greatly appreciated if you could spend some of your time check the status for us. I am very pleased to hear from you on the reviewer’s comments.
Thank you very much for your consideration.
Best regards!
Yours sincerely,
××××××
Corresponding author:
Name: ×××
E-mail: ××××@××××
三、修改稿Cover letter
Dear Dr/ Prof..（写上负责你文章编辑的姓名，显得尊重，因为第一次的投稿不知道具体负责的编辑，只能用通用的Editors）:
On behalf of my co-authors, we thank you very much for giving us an opportunity to revise our manuscript, we appreciate editor and reviewers very much for their positive and constructive comments and suggestions on our manuscript entitled “Paper Title”. (ID: 文章稿号).
We have studied reviewer’s comments carefully and have made revision which marked in red in the paper. We have tried our best to revise our manuscript according to the comments. Attached please find the revised version, which we would like to submit for your kind consideration.
We would like to express our great appreciation to you and reviewers for comments on our paper. Looking forward to hearing from you.
Thank you and best regards.
Yours sincerely,
××××××
Corresponding author:
Name: ×××
E-mail: ××××@××××
四、修改稿回答审稿人的意见（最重要的部分）
List of Responses
Dear Editors and Reviewers:
Thank you for your letter and for the reviewers’comments concerning our manuscript entitled “Paper Title” (ID: 文章稿号). Those comments are all valuable and very helpful for revising and improving our paper, as well as the important guiding significance to our researches. We have studied comments carefully and have made correction which we hope meet with approval. Revised portion are marked in red in the paper. The main corrections in the paper and the responds to the reviewer’s comments are as flowing:
Responds to the reviewer’s comments:
Reviewer #1:
1. Response to comment: (……简要列出意见……)
Response: ××××××
2. Response to comment: (……简要列出意见……)
Response: ××××××
。。。。。。
逐条意见回答，切忌一定不能有遗漏
针对不同的问题有下列几个礼貌术语可适当用用：
We are very sorry for our negligence of ……...
We are very sorry for our incorrect writing ……...
It is really true as Reviewer suggested that……
We have made correction according to the Reviewer’s comments.
We have re-written this part according to the Reviewer’s suggestion
As Reviewer suggested that……
Considering the Reviewer’s suggestion, we have ……
最后特意感谢一下这个审稿人的意见：
Special thanks to you for your good comments.
Reviewer #2:
同上述
Reviewer #3:
××××××
Other changes:
1. Line 60-61, the statements of “……” were corrected as “…………”
2. Line 107, “……” was added
3. Line 129, “……” was deleted
××××××
We tried our best to improve the manuscript and made some changes in the manuscript. These changes will not influence the content and framework of the paper. And here we did not list the changes but marked in red in revised paper.
We appreciate for Editors/Reviewers’ warm work earnestly, and hope that the correction will meet with approval.
Once again, thank you very much for your comments and suggestions.
五、文章接受后可以考虑感谢一下负责你文章的编辑或主编（根据需要）
Dear Prof. ××××××:
Thanks very much for your kind work and consideration on publication of our paper. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.
Thank you and best regards.
Yours sincerely,
××××××
Corresponding author:
Name: ×××
E-mail: ××××@××××
六、询问校稿信件（如果文章接受后时间较长）
Dear ×××:
Sorry for disturbing you. I am not sure if it is the right time to contact you to inquire about the status of our accepted manuscript titled “Paper Title” (ID: 文章稿号), since the copyright agreement for publication has been sent to you two months ago. I am just wondering that how long I can receive the proof of our manuscript from you?
I would be greatly appreciated if you could spend some of your time for a reply. I am very pleased to hear from you.
Thank you very much for your consideration.
Yours sincerely,
××××××
Corresponding author:
Name: ×××
E-mail: ××××@××××
七、文章校稿信件
Dear Mr. ×××:
Thanks very much for your kind letter about the proof of our paper titled “Paper Title” (ID: 文章稿号) for publication in “Journal Name”. We have finished the proof reading and checking carefully, and some corrections about the proof and the answers to the queries are provided below. Corrections:
1. In ****** should be **** (Page ***, Right column, line***)
2. In **** the “*****” should be “****” (Page ****, Right column, line****)
Answers for “author queries”:
1. *********************.
2. **********************
3. **********************
We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know.
Thank you and best regards.
Yours sincerely,
××××××
Corresponding author:
Name: ×××
E-mail: ××××@××××
一、最初投稿Cover letter Dear Editors: We would like to submit the enclosed manuscript entitled “Paper Title”, which we wish to be considered for publication in “Journal Name”. No conflict of interest exits in the submission of this manuscript, and manuscript is approved by all authors for publication. I would like to declare on behalf of my co-authors that the work described was original research that has not been published previously, and not under consideration for publication elsewhere, in whole or in part. All the authors listed have approved the manuscript that is enclosed. In this work, we evaluated …… (简要介绍一下论文的创新性). I hope this paper is suitable for “Journal Name”. The following is a list of possible reviewers for your consideration: 1) Name A E-mail: ××××@×××× 2) Name B E-mail: ××××@×××× We deeply appreciate your consideration of our manuscript, and we look forward to receiving comments from the reviewers. If you have any queries, please don’t hesitate to contact me at the address below. Thank you and best regards. Yours sincerely, ×××××× Corresponding author: Name: ××× E-mail: ××××@×××× 二、催稿信 Dear Prof. ×××: Sorry for disturbing you. I am not sure if it is the right time to contact you to inquire about the status of my submitted manuscript titled “Paper Title”. (ID: 文章稿号), although the status of “With Editor” has been lasting for more than two months, since submitted to journal three months ago. I am just wondering that my manuscript has been sent to reviewers or not?
Dear Editor, Thanks very much for your kind work and consideration on publication of our manuscript entitled "论文标题" (ID ；论文编号). On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers. Moreover, although this is a serious problem because the manuscript is already accepted for publication, we are wishing to add Dr. 新增作者名字as an extra author to the manuscript and the new title page is sent as an attachment. 新增作者名字is a new member of my group and contributed much in the revised version of our manuscript. After we received the referee's comments, he/she did a great job for the expansion of literature review so as to provide a deeper insight into the related published work and hence establish the contribution of this paper with respect to other publications tackling the problem. He/She also recalculated all the noise coefficients with a precision of four digits after the decimal point, as listed in Table II, Table III, Table IV and Table VII. Without her hard work, we could not finish the revised version in several days. However, when I changed the authors' list, I forgot to add her as the fifth author. Would you please to give us a chance to add Qin Gao as a new author to the paper If you give us this chance, we will be grateful. Best wishes, Yours sincerely, XXXXX
英文论文投稿信Cover letter模板 qiusuo BY - 2006-1-17 8:59:00 Dear Editor, We would like to submit the enclosed manuscript entitled "GDNF Acutely Modulates Neuronal Excitability and A-type Potassium Channels in Midbrain Dopaminergic Neurons", which we wish to be considered for publication in Nature Neuroscience. GDNF has long been thought to be a potent neurotrophic factor for the survival of midbrain dopaminergic neurons, which are degenerated in Parkinson’s disease. In this paper, we report an unexpected, acute effect of GDNF on A-type potassium channels, leading to a potentiation of neuronal excitability, in the dopaminergic neurons in culture as well as in adult brain slices. Further, we show that GDNF regulates the K+ channels through a mechanism that involves activation of MAP kinase. Thus, this study has revealed, for the first time, an acute modulation of ion channels by GDNF. Our findings challenge the classic view of GDNF as a long-term survival factor for midbrain dopaminergic neurons, and suggest that the normal function of GDNF is to regulate neuronal excitability, and consequently dopamine release. These results may also have implications in the treatment of Parkinson’s disease. Due to a direct competition and conflict of interest, we request that Drs. XXX of Harvard Univ., and YY of Yale Univ. not be considered as reviewers. With thanks for your consideration, I am Sincerely yours, case2 Dear Editor, We would like to submit the enclosed manuscript entitled "Ca2+-binding protein frequenin mediates GDNF-induced potentiation of Ca2+ channels and transmitter release", which we wish to be considered for publication in Neuron. We believe that two aspects of this manuscript will make it interesting to general readers of Neuron. First, we report that GDNF has a long-term regulatory effect on neurotransmitter release at the neuromuscular synapses. This provides the first physiological evidence for a role of this new family of neurotrophic factors in functional synaptic transmission. Second, we show that the GDNF effect is mediated by enhancing the expression of the Ca2+-binding protein frequenin. Further, GDNF and frequenin facilitate synaptic transmission by enhancing Ca2+ channel activity, leading to an enhancement of Ca2+ influx. Thus, this study has identified, for the first time, a molecular target that mediates the long-term, synaptic action of a
SCI收录材料期刊影响因子及排名 流水浮云 @ 2010-01-07 16:16 Nature自然31.434 Science科学28.103 Nature Material自然（材料）23.132 Nature Nanotechnology自然（纳米技术）20.571 Progress in Materials Science材料科学进展18.132 Nature Physics自然（物理）16.821 Progress in Polymer Science聚合物科学进展16.819 Surface Science Reports表面科学报告12.808 Materials Science & Engineering R-reports材料科学与工程报告12.619 Angewandte Chemie-International Edition应用化学国际版10.879 Nano Letters纳米快报10.371 Advanced Materials先进材料8.191 Journal of the American Chemical Society美国化学会志8.091 Annual Review of Materials Research材料研究年度评论7.947 Physical Review Letters物理评论快报7.180 Advanced Functional Materials先进功能材料 6.808 Advances in Polymer Science聚合物科学发展 6.802 Biomaterials生物材料 6.646 Small微观？ 6.525 Progress in Surface Science表面科学进展 5.429 Chemical Communications化学通信 5.34 MRS Bulletin 材料研究学会（美国）公 告 5.290 Chemistry of Materials材料化学 5.046 Advances in Catalysis先进催化 4.812 Journal of Materials Chemistry材料化学杂志 4.646 Carbon碳 4.373 Crystal Growth & Design晶体生长与设计 4.215 Electrochemistry Communications电化学通讯 4.194 The Journal of Physical Chemistry B 物理化学杂志，B辑：材 料、表面、界面与生物物 4.189
Sample cover letter [Your Name] [Your Affiliation] [Your Address] [Date] Dear [Editor name], I/We wish to submit an original research article entitled “[title of article]” for consideration by [journal name]. I/We confirm that this work is original and has not been published elsewhere, nor is it currently under consideration for publication elsewhere. In this paper, I/we report on / show that _______. This is significant because __________. We believe that this manuscript is appropriate for publication by [journal name]because it… [specific re ference to the journal’s Aims & S cope]. __________. [Please explain in your own words the significance and novelty of the work, the problem that is being addressed, and why the manuscript belongs in this journal. Do not simply insert your abstract into your cover letter! Briefly describe the research you are reporting in your paper, why it is important, and why you think the readership of the journal would be interested in it.] We have no conflicts of interest to disclose. If you feel that the manuscript is appropriate for your journal, we suggest the following reviewers: [List reviewers and contact info, if requested by the journal] Please address all correspondence concerning this manuscript to me at [email address]. Thank you for your consideration of this manuscript. Sincerely, [Your name]
ONE TABLE OF CONTENTS Select an item in the table of contents to go to that topic in the document. LOGGING ON AND OFF THE AUTHOR CENTER (2) LOGGING ON (2) LOGGING OFF (3) FORGOT YOUR PASSWORD? (3) HELP DOCUMENTATION (4) THE WELCOME PAGE (4) INSTRUCTIONS AND FORMS (4) THE AUTHOR DASHBOARD (5) THE MANUSCRIPT SUBMISSION PROCESS (5) IMPORTANT NOTES (6) STEP 1 – TYPE, TITLE, & ABSTRACT (7) SUBMITTING AGENT QUESTION (8) STEP 2 – ATTRIBUTES & KEYWORDS (8) STEP 3 – AUTHORS & INSTITUTIONS (9) STEP 4 – REVIEWERS & EDITORS (10) STEP 5 – DETAILS & COMMENTS (12) STEP 6 – FILE UPLOAD (13) ZIP FILES AND LATEX DOCUMENTS (14) STEP 7 – REVIEW & SUBMIT (15) TIPS FOR AUTHORS SUBMITTING A REVISION (16)
LOGGING ON AND OFF THE AUTHOR CENTER LOGGING ON Each journal’s ScholarOne Manuscripts site has a unique Web address (URL). Typically, you are given the address in an email sent by the journal. If the address is hyperlinked, select the link within the email, or copy and paste into the browser. The journal’s Log In page is displayed. Access to the journal site may be provided in two ways: 1.The journal may create your account and email to you instructions on how to log in and set your User ID and password. 2.Some journals allow their users to create their own accounts. If yours does, there will be a Create Account link in the top right corner of the page, or you can use the New User? Register here just to the right of the Log In. Follow the 3-step process for creating your account. ?Journal-required fields are denoted by the required symbol
中外文核心期刊介绍 及投稿导引
主要内容
一、中外文核心期刊介绍
?理性关注核心期刊 ?什么是核心期刊 ?中国科研评价常用核心期刊
二、核心期刊投稿导引
?有的放矢投稿 ?快乐轻松写稿 ?投稿审稿流程
2
为什么关注核心期刊 ?为了毕业拿学位 EI、SCI收录，高影响因子期刊 ?为了提职称 同行或相关 ?希望研究结果能与同行共享 人员能看到 ?希望研究成果能为社会带来效益 您的文章
核心期刊
3
理性关注中外文核心期刊 核心期刊是期刊中学术水平较高的刊物，是 我国学术评价体系的一个重要组成部分， 但不是全部！
在信息爆炸的年代 ? 在核心期刊中检索并阅读相关文献，可以用最少 的精力获得最大的信息量。 ? 将科研成果发表在核心期刊上可以增加自己的研 究成果被同行看到的几率。
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什么是核心期刊 ?布拉德福定律——核心期刊的起源
对某一主题而言，如果将科学期刊按其刊载某个学科领域 的论文数量以递减顺序排列起来，就可以在所有这些期刊 中区分出载文量最多的‘核心’区和包含着与核心区同等数 量论文的随后几个区，这时核心区和后继各区中所含的期 刊数成 1:a:a2 …… 的关系（ a>1 ）。
常用表述：某个学科领域的论文绝大多数集 中在少数专业期刊之中。
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什么是核心期刊 ?加菲尔德文献集中定律：测定核心期刊的另一种方式
1963年Science Citation index （简称SCI）出版问世，加 菲尔德以SCI数据为统计对象，在1971年对2000种期刊中的10 万参考文献统计后发现，24%的引用频次高的文章出自25种期 刊，50%的引用频次较高的文章出自152种期刊，75%出自767 种期刊，而其余25%的被引文章分布在数量更多的期刊中。
通常表述：论文被引用频次高的期刊也有一个比 较集中的核心区域和一个比较分散的相关区 域。
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英文投稿信的客套话 一、投稿信 往国外杂志投稿,就是写COVER LETTER,主要内容应该有: 简述所投稿件的核心内容、主要发现和意义，拟投期刊，对稿件处理有无特殊要 求等（如“not to review” list）。另外，请附上主要作者的中文姓名、通讯 地址、电话、传真和e-mail地址。此外有的杂志要求推荐几位审稿人及其联系 方式。以及谁已经阅读过该文（当然是牛人）。 最后给一个模板: Dear Dr. 主编name: We submit our manuscript entitled " 文章title" to 杂志名for publication. 接着简单介绍你文章的主要创新点和意义，不易过多，但要突出新意和关键点。All authors have seen the manuscript and approved to submit to your journal. Thank you very much for your attention and consideration. Sincerely yours, 通讯作者 [search]投稿信[/search] 1. Dear Dr. Defendi ML: I am sending a manuscript entitled “” by –which I should like to submit for possible publication in the journal of - .Yours sincerely 2. Dear Dr. A: Enclosed is a manuscript entitled “” by sb, which we are submitting for publication in the journal of - . We have chosen this journal because it deals with - . We believe that sth would be of intere st to the journal’s readers. 3. Dear Dr. A: Please find enclosed for your review an original research article, “” by sb. All authors have read and approve this version of the article, and due care has been taken to ensure the integrity of the work. No part of this paper has published or submitted elsewhere. No conflict of interest exits in the submission of this manuscript, and we have attached to this letter the signed letter granting us permission to use Figure 1 from another source. We appreciate your consideration of our manuscript, and we look forward to receiving comments from the reviewers. 二、询问有无收到稿件 Dear Editors,
英文投稿邮件写作模板 一、最初投稿Cover letter Dear Editors: We would like to submit the enclosed manuscript entitled “Paper Title”, which we wish to be considered for publication in “Journal Name”. No conflict of interest exits in the submission of this manuscript, and manuscript is approved by all authors for publication. I would like to declare on behalf of my co-authors that the work described was original research that has not been published previously, and not under consideration for publication elsewhere, in whole or in part. All the authors listed have approved the manuscript that is enclosed. In this work, we evaluated …… (简要介绍一下论文的创新性). I hope this paper is suitable for “Journal Name”. The following is a list of possible reviewers for your consideration: 1) Name AE-mail: ××××@×××× 2) Name BE-mail: ××××@×××× We deeply appreciate your consideration of our
英文材料期刊简介 Journal of Alloys and Compounds《合金与化合物杂志》瑞士 ISSN:0925-8388，1959年创刊，全年36期，Elsevier Science出版社出版，SCI收录期刊，SCI2003年影响因子1.080。国际性材料科学和固体化学与固体物理学杂志。刊载稀有金属及其化合物、合金的实验和理论研究论文、会议报告、简讯与书评。文章多用英文发表。 Journal of Composites for Construction《建筑复合材料杂志》美国 ISSN:1090-0268，1997年创刊，每年4期，American Society of Civil Engineers,USA出版。刊载有关建筑用合成纤维增强复合材料的研究论文。SCI、EI收录期刊，SCI2003年影响因子1.234，被引频次249、即年指标0.125、年载文量40。2003年EI收录91篇。EI收录期刊，EI2001年收录25篇。 Journal of Materials in Civil Engineering《土木工程材料杂志》美国 ISSN:0899-1561，1989年创刊，每年6期，American Society of Civil Engineers,USA出版。刊载土建材料的开发、加工与现场生产、特性评价、应用和性能等方面的研究论文。SCI、EI收录期刊，2002年SCI影响因子0.346、被引频次193、即年指标0.015、年载文量66、被引半衰期4.9。EI2002年收录66篇。 Journal of the European Ceramic Society《欧洲陶瓷学会志》英国 ISSN:0955-2219，1985年创刊，全年16期，Elsevier Science出版社出版，SCI、EI收录期刊，SCI2003年影响因子1.248，2003年EI收录396篇。主要发表研究陶瓷材料结构、特性和加工的原始论文。 Journal of Magnetism and Magnetic Materials《磁学和磁性材料杂志》荷兰 ISSN:0304-8853，1976年创刊，全年45期，Elsevier Science出版社出版，SCI、EI收录期刊，SCI2003年影响因子0.910，2003年EI收录909篇。刊载磁学理论和磁性材料技术与应用等方面的研究论文、简报及札记。 Journal of Materials Processing Technology《材料加工技术杂志》瑞士 ISSN:0924-0136，1977年创刊，全年36期，Elsevier Science出版社出版，1989年刊名为Journal of Materials Processing Technology。SCI、EI收录期刊，SCI2003年影响因子0.450，2003年EI收录928篇。刊载计算机在金属变形和工艺过程模拟中的应用，以及计算机辅助成形系统和金属加工工艺装置的计算机辅助设计等方面的研究论文和快报。 Journal of the Mechanics and Physics of Solids《固体力学与固体物理学杂志》英国 ISSN:0022-5096，1953年创刊，全年12期，Elsevier Science出版社出版，SCI、EI收录期刊，SCI2003年影响因子2.885，2003年EI收录100篇。刊载结构材料特性方面的研究论文和实验报告。 Journal of Non-Crystalline Solids《非晶性固体杂志》荷兰 ISSN:0022-3093，1969年创刊，全年54期，Elsevier Science出版社出版，SCI、EI收录期刊，SCI2003年影响因子1.563，2003年EI收录665篇。刊载氧化物与非氧化物玻璃、非
Cover Letter对于论文投稿至关重要。以下是小编总结的SCI 论文投稿全过程 中要用到的 cover letter等投稿信模板，供大家分享借鉴。 一、最初投稿Cover letter Dear Editors: We would like to submit the enclosed manuscript entitled“ Paper Title” , whi we wish to be considered for publication in“ JournalconflictNameof” . No interest exits in the submission of this manuscript, and manuscript is approved by all authors for publication. I would like to declare on behalf of my co-authors that the work described was original research that has not been published previously, and not under consideration for publication elsewhere, in whole or in part. All the authors listed have approved the manuscript that is enclosed. In this work, we evaluated简??要介绍(一下论文的创新性). I hope this paper is suitable for“ Journal Name”. The following is a list of possible reviewers for your consideration: 1)Name A E-mail: ××@× ××× 2)Name B E-mail: ××@× ××× We deeply appreciate your consideration of our manuscript, and we look forward to receiving comments from the reviewers. If you have any queries, please don ’ t hesitate to contact me at the address below. Thank you and best regards. Yours sincerely, ×××××× Corresponding author: Name: ××× E-mail:×××@× ××× 二、催稿信 Dear Prof.××:
环境类外文期刊（SCI\EI）投稿指南 一．《SCI》收录的外文科技期刊 1. Critical Reviews in Environmental Science and Technology. 1970. 4/yr. (环境科学与技术评论) ED: Terry J. Logan, Department of Agronomy, Ohio state University, Columbus, OH, USA. https://www.doczj.com/doc/ae12270713.html,/ 715B0006 ISSN 1064-3389 2. Journal of the Institute of Environmental Sciences and Technology. 1958. 6/ry. (环境科学与技术学会志) * ED: Institute of Environmental Sciences and Technology, 940 E. Northwest Highway, Mt. Prospect , IL 60056-3422, USA. Tel: 847 255 1561 Fax: 847 255 1699 E-mail: InstEnvSci@https://www.doczj.com/doc/ae12270713.html, https://www.doczj.com/doc/ae12270713.html,/ 715B0007 ISSN 1098-4321 3. Ecotoxicology and Environmental Safety; Environmental Research Section B. 1977. 9/yr. (生态毒物学与环境安全) ED：International Society of Ecotoxicology and Environmental Safety.Professor Dr.Miki Goto, Institute of Ecotoxicology, GakushuinUniversity, 5-1 Mejiro 1 chome, Toshima-ku, Tokyo 171, Japan E-mail: apcs@https://www.doczj.com/doc/ae12270713.html, https://www.doczj.com/doc/ae12270713.html,/ 715B0010 ISSN 0147-6513 4.Reviews of Environmental Contamination and Toxicology. 1962. 4/yrSpringer-verlag,175 Fifth Ave, New York, NY,10010 (环境污染与毒物学评论) 715B0013 ISSN 0179-5953 5．Environmental Progress. 1982. 4/yr. American Institute of ChemicalEngineers, 34E.47th St. New York, NY 10017-2395. USA. (环境进展) * Tel: 212 705 8100 Fax: 212 705 8400 https://www.doczj.com/doc/ae12270713.html,/publications/package.htm https://www.doczj.com/doc/ae12270713.html,/ 715B0014 ISSN 0278-4491 6. Water Environmental Research. 1989. 7/yr. Water Environmental Federation, 601 Wythe ST., Alexandria, VA 22314-1994, USA. (水环境研究) * Fax: 703 684 2492
英文论文投稿信Cover?letter模板 qiusuo BY - 2006-1-17 8:59:00 Dear Editor, We would like to submit the enclosed manuscript entitled "GDNF Acutely Modulates Neuronal Excitability and A-type Potassium Channels in Midbrain Dopaminergic Neurons", which we wish to be considered for publication in Nature Neuroscience. GDNF has long been thought to be a potent neurotrophic factor for the survival of midbrain dopaminergic neurons, which are degenerated in Parkinson’s disease. In this paper, we report an unexpected, acute effect of GDNF on A-type potassium channels, leading to a potentiation of neuronal excitability, in the dopaminergic neurons in culture as well as in adult brain slices. Further, we show that GDNF regulates the K+ channels through a mechanism that involves activation of MAP kinase. Thus, this study has revealed, for the first time, an acute modulation of ion channels by GDNF. Our findings challenge the classic view of GDNF as a long-term survival factor for midbrain dopaminergic neurons, and suggest that the normal function of GDNF is to regulate neuronal excitability, and consequently dopamine release. These results may also have implications in the treatment of Parkinson’s disease. Due to a direct competition and conflict of interest, we request that Drs. XXX of Harvard Univ., and YY of Yale Univ. not be considered as reviewers. With thanks for your consideration, I am Sincerely yours, case2 Dear Editor, We would like to submit the enclosed manuscript entitled "Ca2+-binding protein frequenin mediates GDNF-induced potentiation of Ca2+ channels and transmitter release", which we wish to be considered for publication in Neuron. We believe that two aspects of this manuscript will make it interesting to general readers of Neuron. First, we report that GDNF has a long-term regulatory effect on neurotransmitter release at the neuromuscular synapses. This provides the first physiological evidence for a role of this new family of neurotrophic factors in functional synaptic transmission. Second, we show that the GDNF effect is mediated by enhancing the expression of the Ca2+-binding protein frequenin. Further, GDNF and frequenin facilitate synaptic transmission by enhancing Ca2+ channel activity, leading to an enhancement of Ca2+ influx. Thus, this study has identified, for the first time, a molecular target that mediates the long-term, synaptic action of a neurotrophic factor. Our findings may also have general implications in the cell biology of neurotransmitter release. [0630][投稿写作]某杂志给出的标准Sample Cover Letter[the example used is the IJEB]